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The top seed in the East Region, the Pittsburgh Panthers, are set to do battle with the East Tennessee State Buccaneers on Friday at 2:55pm ET. The game will be played at the University of Dayton Arena in Dayton, Ohio. The heavily favored Panthers will go on to meet either Oklahoma State or Tennessee if they are able to overcome East Tennessee.

East Tennessee State vs Pittsburgh NCAA Bracket Predictions at SBGglobal.com have the Panthers listed as a -19.5 against the spread favorite.

Pittsburgh finished second in the Big East this season after going 15-3 in conference play and 28-4 overall. Despite the Panthers supremacy in regular season action, they were unable to get by the West Virginia Mountaineers in the conference tournament last week. Pitt fell 60-74 to Bob Huggins squad, giving them just their second loss in their last 12 games.

The Panthers, who are listed at +150 moneyline odds to win the East Region, are 2-1 in neutral site games this season. Pitt has three starters that average double figures in scoring, but they are led by forward DeJuan Blair. The big man posted an average of 15.6 points per game this year while reeling in an average of 12.2 rebounds per game .

East Tennessee finished in second place in the Atlantic Sun conference regular season standings with a 14-6 league record. The Bucs, winners of five straight games, ran their win total to 23 on March 7th when they beat Jacksonville 85-68 to win the Atlantic Sun conference tournament. The victory gave East Tennessee an automatic NCAA Tournament bid.

The Buccaneers , who averaged 78.6 points per game this year, are listed at +4500 moneyline odds to win the East Regional. East Tennessee, which is 3-2 in neutral site games, is led by senior forward Kevin Tiggs. Tiggs averaged 21.5 points and 4.8 rebounds per game during regular season.

SBGglobal.com's East Tennessee State vs Pittsburgh NCAA Bracket Predictions:

East Tennessee State Buccaneers +19.5 (-110), Over 148 (-110)

Pittsburgh Panthers -19.5 (-110), Under 148 (-110)

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