Cincinnati vs Louisville 2010 College Football Predictions, 2010 College Football Odds & 2010 College Football Picks: The Louisville Cardinals will look to make it three straight tomorrow night when they host conference rival Cincinnati at Papa John's Cardinal Stadium. The two Big East cohorts are scheduled to kickoff at 8:00pm ET on ESPN. 2010 College Football Predictions, Odds & Picks at BetUS.com have the Bearcats listed as a -2.5 against the spread road favorite; the game total is set at 58.
Cincinnati comes into this rivalry contest with a 2-3 record after fighting through a non-conference schedule that included 
meetings with Fresno State, North Carolina State, and Oklahoma. The Bearcats are coming off a win, though, as they snapped a two game skid with a 45-3 route of the Miami RedHawks.
Butch Jones' troops rolled on offense, producing 29 first downs, 607 total yards, and a staggering 384 rush yards on 46 carries. Cincinnati's big three, quarterback Zach Collaros, running back Isaiah Pead, and wide receiver Armon Binns, were key in the shellacking. Collaros completed 14-of-17 passes for 216 yards and three touchdowns, Pead rushed for 197 yards and one score on 10 touches, and Binns caught five passes for 115 yards and two touchdowns.
Louisville rides a two game win streak into tomorrow evening's clash with Cincinnati, having beat Arkansas State and Memphis by a combined score of 90-24. Charlie Strong's squad, which suffered losses to Kentucky and Oregon State, had its best game of the year last weekend, smashing the Tigers 56-0.
Senior quarterback Adam Froman, who has thrown seven touchdowns to one interception in his last two outings, played brilliantly in the win, completing 12 of his 16 passes for 235 yards and four touchdowns. Running back Bilal Powell, whose 689 rush yards ranks ninth in the FBS, also turned in a stellar performance, rushing for 204 yards and two touchdowns on 18 carries.
The Cardinals defense limited Memphis to 223 total yards in 33:14 and a 1.1 yards per carry average for the game.
The Bearcats are 3-7 straight up in their last 10 games against Louisville; however, they have won the last two in this series, including a 41-10 beat down last year in Cincinnati.
College Football Predictions Betting Trend: The Cardinals are 1-6 straight up and against the spread in their last seven games as a home underdog with a spread between 0 and 3.5.
BetUS.com Cincinnati vs Louisville 2010 College Football Predictions, Odds & Picks:
Cincinnati Bearcats -2.5 (-115), Over 58 (-110), -145 (Moneyline)
Louisville Cardinals +2.5 (-105), Under 58 (-110), +125 (Moneyline)
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