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Louisville vs. Connecticut College Football Picks: The Louisville Cardinals and Connecticut Huskies football teams will be looking for their first BIG EAST win when they play Saturday ( Noon ET) at Rentschler Field in East Hartford, Conn.

College football picks oddsmakers at SBGglobal.com.com lists Connecticut as 13-chalk ATS favorite with a 45 total. Oddsmakers have opted to leave moneyline odds OFF the SGB Global board.

The Cardinals and Huskies will meet for the sixth time when the schools square off this Saturday. Louisville leads the overall series 3-2, but has dropped the last two encounters to Connecticut, including a 26-21 decision at Papa John's Cardinal Stadium in 2008. Louisville dropped its last visit to Connecticut 21-17 on a rainy night in 2007. The Cardinals are 1-1 all-time at Connecticut with their only win a 30-20 decision in 2005.

Connecticut dropped its BIG EAST opener against Pittsburgh last Saturday 24-21 at Heinz Field when Dan Hutchins booted an 18-yard field goal in the final seconds of the game. Connecticut gave up 11 points in the fourth quarter in the loss. The Huskies covered as a 6.5-point road underdog while the final score played under the 47-point total.

Louisville just got past Southern Mississippi, winning 25-23 at Papa John's Cardinal Stadium in Week 6. Louisville covered as a 2-point home underdog while the final score played under the 49.5-point total.

College Football Picks: Take the Huskies ATS -13 in this one.

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