Alabama Crimson Tide vs. Mississippi State Bulldogs College Football Pick: Betting Line Alabama by -22 (Total 41); Television-ESPN; Kickoff 6:45 pm ET; Bryant-Denny Stadium, Tuscaloosa, Ala. Betting odds provided by BetUS.com:

No. 1 ranked Alabama rolls into its game with old SEC rival Mississippi State at Bryant-Denny Stadium in Tuscasloosa, Ala., on Saturday with plenty to think about. First off, the Tide is coming off a huge road win in week 12 over LSU and must be on guard to avoid any let-down this week. While this weeks opponent might not be as quality of an opponent as LSU was last week, the Bulldogs have still managed to defeat Alabama the past two years and the teams have split the last 12. The Crimson Tide owns a 72-17-3 all-time series lead.

Oddsmakers at online sportsbook BetUS.com do not expect much of a let down having installed the Crimson Tide as 22-chalk ATS and -1800 moneyline favorites with a 41 total.

While the Bulldogs have an unimpressive overall record, they have managed to play competitive football. Gamblers must be aware that MSU has only given up an average of 21.2 points per game. Today's affair with Alabama is expected to take on a defensive tone.

Only once this season, at LSU on Sep. 27, did oddsmakers list MSU as more than three touchdown underdogs (+23). The Bulldogs lost the game SU but easily covered the spread 24-34.

MSU is 2-0 ATS this season in games where it was a double-digit underdog.

Handicapper Reno Gold looks forward to another stellar week of college football picks. Reno has a solid (Side) pick for tonight's Alabama vs. Mississippi State game at Bryant-Denny Stadium in Tuscaloosa. Reno Gold, a two-time online sports handicapping champion, gives a 1000% guarantee on his picks or the next one is free.

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