San Francisco 49ers vs San Diego Chargers NFL Predictions, NFL Odds & NFL Picks: The Forty-Niners are in San Diego this evening to take on the Chargers at Qualcomm Stadium. The final game of the 2009 NFL preseason is set to kick off at 10:00pm ET. Sportsbetting.com has the Chargers listed as a -4.5 against the spread home favorite in tonight's meeting with the undefeated Forty-Niners.
San Diego Chargers: The Chargers fell to 1-2 in exhibition play last 
Saturday, losing 24-27 to Atlanta at the Georgia Dome. Despite the loss, Norv Turner's team had its way on offense in the first half, building a 21-13 halftime lead.
Quarterback Phillip Rivers continued his near flawless preseason play, completing 10-of-15 for 185 yards and a touchdown. Rivers was instrumental in leading San Diego to 261 first half yards and three 75 plus yard touchdown drives.
The Chargers finished the game with 438 yards. They also averaged over 10 yards per pass and converted 11 of 16 third down opportunities.
San Francisco 49ers: Mike Singletary's bunch worked their record to a perfect 3-0 on Saturday by getting past the Cowboys 20-13 in Dallas. The Forty-Niners showing was a near opposite of the Chargers as they trailed 10-3 after an unimpressive first half.
Starting quarterback Shaun Hill had a lackluster outing, completing just nine of his 17 pass attempts for 79 yards. There were positives on offense, though, as rookie quarterback Nate Davis hit on 10-of-15 for 132 yards. Running back Glen Coffee continued his torrid preseason run too, catching three passes for 27 yards while rushing eight times for 34 yards.
Sportsbetting.com San Francisco 49ers vs San Diego Chargers NFL Predictions, Odds & NFL Picks
San Francisco 49ers +4.5 (-110), Over 36.5 (-110)
San Diego Chargers -4.5 (-110), Under 36.5 (-110)
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