Philadelphia Eagles vs San Francisco 49ers 2010 NFL Odds, Picks & Predictions

Philadelphia Eagles vs San Francisco 49ers 2010 NFL Odds, 2010 NFL Picks & 2010 NFL Predictions: The Forty-Niners will host the Philadelphia Eagles tonight in hopes of securing their first win of the season. This evening's NFC clash is scheduled to get underway at 8:20pm ET at Candlestick Park in San Francisco; it will be televised live on NBC's Sunday Night Football. 2010 NFL Odds, Picks & Predictions at have the Niners listed as a -3.5 against the spread home favorite and the game total set at 38.

Eagles Breakdown: Philadelphia had a rough outing last weekend at Lincoln Financial Field, losing 17-12 to NFC East rivaPhiladelphia Eagles vs San Francisco 49ers 2010 NFL Odds, Picks & Predictionsl Washington. Not only did the Eagles lose the game, dropping their record to 2-2 on the season, they also lost freshly minted starting quarterback Michael Vick to a first quarter rib injury. Vick's absence was reflected on the scoreboard, but not necessarily on the stat sheet as Philly finished the game with 353 total yards.

Kevin Kolb completed 22-of-35 passes for 201 yards, one touchdown, and one interception in relief of his former backup while the Eagles rushing attack averaged 4.4 yards per carry on 25 touches.

Philadelphia's defense held Donovan McNabb and the Redskins to 16 first downs and 293 total yards; however, Washington did move the ball on the ground against the unit, racking up 169 yards on 35 carries.

Forty-Niners Breakdown: San Francisco saw its record drop to 0-4 last weekend in Atlanta with a 16-14 Falcons victory. Once again, the Niners aided their opposition's cause as Alex Smith threw two interceptions and cornerback Nate Clements fumbled on an interception return.

In addition to the mistakes, San Francisco had difficulty moving the ball against the Falcons defense, finishing the game with 262 total yards. The Niners also failed to top the 300 yard mark in their week three loss to the Chiefs.

San Francisco's defense did rebound from its poor effort against the Chiefs, holding the Falcons to 3.4 yards per carry while picking Matt Ryan off twice.

NFL Picks Betting Trend: The Forty-Niners are 8-2 straight up and 7-3 against the spread in their last 10 games as a home favorite in the month of October. Philadelphia Eagles vs San Francisco 49ers 2010 NFL Odds, Picks & Predictions:

Philadelphia Eagles +3.5 (-120), Over 38 (-110), +155 (Moneyline)

San Francisco 49ers -3.5 (+100), Under 38 (-110), -175 (Moneyline)

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