Chicago Bears vs San Francisco 49ers NFL Picks, Predictions & Odds

Chicago Bears vs San Francisco 49ers NFL Picks, NFL Predictions & NFL Odds: The Chicago Bears and the San Francisco 49ers kickoff the NFL's mid-season Thursday night action this week with a battle at Candlstick Park in San Francisco. The game, which features Niners Head Coach Mike Singletary trying to beat his old club, is set to kickoff at 8:30pm ET on the NFL Network. NFL Picks at have San Francisco listed as a -3 against the spread home favorite.

Bears Breakdown: Chicago lost for the third time in its last four games on Sunday, falling at home 21-41 to the Arizona Chicago Bears vs San Francisco 49ers NFL Picks, Predictions & OddsCardinals. The Bears, as a result, come into this week's game with a 4-4 overall record and a third place position in the NFC North standings. Lovie Smith's defense gave up 27 first downs and 438 yards to Arizona, and, more shockingly, allowed the pass oriented Cards to run for 182 yards at 5.9 yards per carry. Jay Cutler led the offense to 417 total yards, but he was unable to keep pace with Kurt Warner's five touchdown passes.

The Bears are 1-3 on the road this season where they average 16 points per game and give up an average of 26.5 in return.

Forty Niners Breakdown: While Chicago has fallen on hard times, San Francisco has hit the skids with even greater ferocity as the team has dropped four straight games. Their latest losing effort took place last Sunday at Candlestick where they fell to the Titans by a score of 27-34. Singletary's troops had more first downs and more yardage than did Tennessee, but they were unable to overcome four turnovers. Quarterback Alex Smith , who completed 29-of-45 passes for 286 yards, tossed three interceptions in the loss, including two in a back breaking fourth quarter. 

San Francisco is 2-2 at home this season, but they have lost their last two games in the Bay Area by a combined score of 37-79. 

NFL Picks Betting Trend: The Forty Niners are 0-4 straight up and against the spread (dating back to 1996) as a home favorite with a spread between 0 and 3.5 and total between 41.5 and 44 (the Under 3-1). Chicago Bears vs San Francisco 49ers NFL Picks, Predictions & Odds:

Chicago Bears +3 (-105), Over 43 (-110), +145 (Moneyline)

San Francisco 49ers -3 (-115), Under 43 (-110), -165 (Moneyline)

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