The Buffalo Bills finally got a win after dropping four straight, while the San Francisco 49ers lost last week after winning their first game in six tries. The Buffalo Bills (6-5) host the San Francisco 49ers (3-8), Sunday Nov 30, at Ralph Wilson Stadium for some hard hitting NFL Week 13 action. NFL oddsmakers at Sportsbook.com have the Bills as -7 point home favs over the Niners with the over/under set at 42 ½ points. Get your Buffalo Bills vs San Francisco 49ers NFL Week 13 Picks in now at Sportsbook.com
The Bills beat the Chiefs 54-31 on the road in Week 12. QB Trent Edwards made 24 of 32 passes for 273 yards with two touchdowns and no interceptions; he has 10 touchdown passes for 2,226 yards with 10 interceptions in 11 starts. Their top rusher on the day was RB Marshawn Lynch with 20 carries for 79 yards with one touchdown. Their top receiver on the day was WR Lee Evans with five catches for 110 yards, while WR Josh Reed and TE Derek Schouman each added a touchdown. The Bills are averaging 24.8 ppg and their giving up an average 22.6 ppg. At home they are 3-2 SU where they average 25 ppg and they give up an average 20.4 ppg. Their overall offense is ranked 19th in the league averaging 3019 yards a game, thanks to their 13th ranked passing game that’s good for 213 yards per-game. Their running game sits poorly ranked 22nd in the league averaging 106 yards a game. RB Marshawn Lynch leads the Bills with eight touchdowns. Their overall defense is ranked 16th in the league allowing 325 yards per-game, thanks to their 16th ranked pass defense that allows 211 yards a game, they are average against the rush with a 20th ranked rush defense that gives up an average 114 yards per-game. The Bills are 5-6 ATS and 6-4 over/under.
The Niners lost to the Cowboys 22-35 on the road in Week 12. QB Shaun Hill made 21 of 33 passes for 303 yards with two touchdown passes and an interception; he has seven touchdown passes for 906 yards with three interceptions in four starts. Their top rusher on the day was RB Frank Gore with 14 carries for 26 yards. Their top receiver on the day was WR Isaac Bruce with eight catches for 125 yards with a touchdown, while WR DeShaun Foster added a touchdown. The Niners are averaging 22.9 ppg and they give up an average 28.2 ppg. On the road they are 1-4 SU where they average 22.6 ppg and they give up an average 30.8 ppg. Their overall offense is ranked 22nd in the league averaging 314 yards a game, thanks to their 15th ranked passing game that’s good for 212 yards per-game. Their running game is ranked 23rd in the league averaging 101 yards a game. RB Frank Gore leads the Niners with seven touchdowns. Their overall defense is ranked 22nd in the league allowing 347 yards per-game, no thanks to their 29th ranked pass defense that allows 243 yards a game, they are average against the rush with a 14th ranked rush defense that gives up an average 103 yards per-game. The Niners are 4-7 ATS and 7-3 over/under.
Recent Trends to Consider:
- Bills are 6-0 ATS in their last 6 games in Week 13.
- Bills are 13-3 ATS in their last 16 home games vs. a team with a losing road record.
- Bills are 24-6-1 ATS vs. a team with a losing record.
- 49ers are 1-4 ATS vs. a team with a winning record.
- 49ers are 1-4 ATS in their last 5 games after allowing more than 250 yards passing in their previous game.
- 49ers are 1-4 ATS in their last 5 road games vs. a team with a winning home record.
- 49ers are 1-4 ATS in their last 5 games following a ATS loss.
- Over is 7-1-1 in Bills last 9 home games.
Buffalo Bills vs San Francisco 49ers NFL Week 13 Picks
When: Sun, Nov 30, 2008 1:00 PM ET
Line: Sportsbook.com
Pick: Bills -7
Point-Spreads.com Buffalo Bills vs San Francisco 49ers NFL Week 13 Picks- Bills -7
The Bottom Line: The Bills got some great practice against the Chiefs last week and they’ll carry that style of play against the Niners. Go Bills! Get your Buffalo Bills vs San Francisco 49ers NFL Week 13 Picks in now at Sportsbook.com and receive a 10% sign-up bonus on your initial deposit!




