NFL Week 12 Picks on the San Francisco 49ers vs Arizona Cardinals Betting Odds: The struggling Arizona Cardinals host the San Francisco 49ers, Monday Nov 29, as the Niners try for their first win away from home and the Cardinals try to avoid dropping six straight. The Niners have won their last two meetings. NFL oddsmakers at SPORTSBOOK.com have the Niners as -1 point road favorites over the Cardinals while the game's total has been posted at 40.5 points. Be sure to get the latest NFL Spreads for your NFL Week 12 Picks on the San Francisco 49ers vs Arizona Cardinals Betting Odds.
The Niners (3-7) (0-4 V) got shutout by Tampa Bay 0-21, at home, in Week 11 and sit tied for third in the NFC West, with Arizona. QB Troy Smith completed 16 of 31 passes for 148 yards with one interception and had five carries for 45 yards. RB Frank Gore had 12 carries for 23 yards, while WR Josh Morgan made four catches for 51 yards. The Niners had two sacks and no interceptions. If Troy Smith is to remain secure as the team's starter, the fourth-year veteran needs to return to the winning form he displayed in his first two starts. The 49ers would like to see the Troy Smith who threw for 552 yards with no turnovers in his first two starts against the Denver Broncos and St. Louis. Smith had success rolling out and throwing on the run in those games, and his play-action style fit in nicely with the 49ers' power rushing approach that features running back Frank Gore. Over the past twelve contests between the two teams, only three have been decided by more than a touchdown. And in games at Arizona, no game has been won by more than six points since 1999. RB Frank Gore has 10 rushing TDs in his last eight games against the Cardinals and Justin Smith has three sacks in his past three games. The Niners offense is ranked 25th overall (313ypg) with a 19th ranked pass game (217ypg) and a 25th ranked running game (95ypg). They score the 31st least amount of points per-game (16ppg).The Niners go up against the Cardinals 29th ranked defense (396ypg), their 27th ranked pass rush (261ypg) and their 28th ranked rush defense (135ypg). The Cards defense gives up the NFL’s most points per-game (29ppg).
The Cardinals (6-4) (2-2 H) lost at Kansas City 13-31, in Week 11 and sit tied for third in the NFC West, with San Francisco. QB Derek Anderson made 25 of 46 passes for 295 yards with a TD, while RB Timothy Hightower had 12 carries for 62 yards. WR Steve Breaston made five catches for 92 yards and Larry Fitzgerald made six catches for 90 yards with a TD. Their defense got no sacks or interceptions. OLB Will Davis broke his left leg against the Chiefs and is expected to be out for the season. Coach Whisenhunt said he expects Clark Haggans back this week and, with rookie O'Brien Schofield now the backup. RB Beanie Wells has a rushing TD in five straight division games, while Joey Porter is third among active players with 97 sacks. The Cardinals have the NFL’s second worst offense (275ypg) with the NFL’s third worst ranked pass game (191ypg) and a 28th ranked ground game (84ypg). Larry Fitzgerald leads their offense with five TD’s. The Cardinals battle against the Niners 13th ranked defense (328ypg), their 17th ranked pass rush (221ypg) and their 15th ranked rush defense (106ypg). The Niners give up the 16th most amount of points per-game (21.9ppg).
Recent Trends to Consider:
- 49ers are 4-0 ATS in their last 4 meetings in Arizona.
- Over is 5-1 in the last 6 meetings in Arizona.
- 49ers are 4-1 ATS in their last 5 meetings.
- Underdog is 7-1 ATS in their last 8 meetings.
- Road team is 8-1 ATS in their last 9 meetings.
- 49ers are 5-0 ATS in their last 5 games after allowing more than 150 yards rushing in their previous game.
- 49ers are 17-5 ATS in their last 22 Monday games.
San Francisco 49ers vs Arizona Cardinals
When: Mon, Nov 29, 8:30 PM ET
Line: SPORTSBOOK.com
Pick: Niners -1
Point-Spreads.com recommends you get your NFL Picks Week 12 in early!
The Bottom Line: It’s the perfect time for the Niners to win. Be sure to get your NFL Week 12 Picks: San Francisco 49ers vs Arizona Cardinals Betting Odds in now at SPORTSBOOK.com




