National Football League Lines
Point Spread / TotalMoney Line
| Line moves colors: < 10 min. < 20 min. < 30 min. < 60 min. | ||||||||||
| Last update | 21:20 | 21:20 | 21:20 | 21:20 | 21:20 | 21:20 | ||||
| Date | # | Teams | Opening | Score |  |  |  |  |  |  |
| 11/22 13:05 | 407 408 | Cleveland Browns Detroit Lions | +160 -190 | +160 -190 | +160 -180 | +165 -190 | +160 -190 | +162 -182 | +160 -190 | |
| 11/22 13:05 | 409 410 | Buffalo Bills Jacksonville Jaguars | +315 -375 | +320 -400 | +300 -400 | +320 -400 | +320 -400 | +310 -380 | +315 -375 | |
| 11/22 13:05 | 411 412 | Pittsburgh Steelers Kansas City Chiefs | -525 +425 | -600 +400 | -600 +400 | -550 +425 | -550 +425 | -500 +400 | -550 +450 | |
| 11/22 13:05 | 413 414 | Indianapolis Colts Baltimore Ravens | -110 -110 | -125 +105 | -122 +102 | -125 +105 | ||||
| 11/22 13:05 | 415 416 | Atlanta Falcons New York Giants | +215 -255 | +250 -300 | +250 -300 | +255 -310 | +250 -300 | +255 -310 | +260 -310 | |
| 11/22 13:05 | 417 418 | San Francisco 49ers Green Bay Packers | +250 -300 | +240 -280 | +245 -290 | +240 -280 | +235 -275 | +240 -280 | +255 -305 | |
| 11/22 13:05 | 419 420 | Seattle Seahawks Minnesota Vikings | +450 -550 | +400 -600 | +425 -550 | +400 -500 | +400 -500 | +450 -550 | ||
| 11/22 13:05 | 421 422 | Washington Redskins Dallas Cowboys | +450 -550 | +400 -600 | +425 -550 | +425 -550 | +435 -560 | +475 -600 | ||
| 11/22 13:05 | 423 424 | New Orleans Saints Tampa Bay Buccaneers | -550 +450 | -600 +400 | -550 +425 | -550 +425 | -550 +425 | -550 +450 | ||
| 11/22 16:10 | 425 426 | Arizona Cardinals St. Louis Rams | -400 +330 | -400 +320 | -450 +325 | -400 +320 | -400 +320 | -405 +325 | -415 +345 | |
| 11/22 16:20 | 427 428 | New York Jets New England Patriots | +425 -525 | +400 -600 | +450 -600 | +425 -550 | +490 -640 | +495 -620 | ||
| 11/22 16:20 | 429 430 | Cincinnati Bengals Oakland Raiders | -450 +370 | -500 +350 | -500 +350 | -450 +350 | -450 +350 | -430 +350 | -450 +370 | |
| 11/22 20:25 | 433 434 | Philadelphia Eagles Chicago Bears | -160 +140 | -160 +140 | -160 +140 | -155 +135 | -155 +135 | -165 +145 | -165 +145 | |
| 11/23 20:40 | 435 436 | Tennessee Titans Houston Texans | +190 -230 | +190 -230 | +180 -220 | +180 -220 | +190 -230 | +175 -210 | +185 -215 | |